Dextromethorphan FDA Link Generic

Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.

Also Known As:

Racemethorphan; Delsym; Dextromethorphan Hydrobromide; Dextromethorphan Hydrochloride; Dextromethorphan Hydrobromide, (+-)-Isomer; Dextromethorphan Hydrobromide, Monohydrate; Dextromethorphan, (+-)-Isomer; Hydrobromide, Dextromethorphan; Hydrochloride, Dextromethorphan; d-Methorphan; Morphinan, 3-methoxy-17-methyl-, (9alpha,13alpha,14alpha)-

Pharmalogical Action Categories:

Antitussive Agents
Excitatory Amino Acid Antagonists

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Opiate Alkaloids: 5944
    - Morphinans: 33
      - Dextromethorphan: 753
- Bridged-Ring Heterocyclic Compounds
  - Morphinans: 33
    - Dextromethorphan: 753
- Fused-Ring Heterocyclic Compounds
  - 4 or More Rings Heterocyclic Compounds
    - Morphinans: 33
      - Dextromethorphan: 753
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Phenanthrenes: 27
    - Morphinans: 33
      - Dextromethorphan: 753

G S Dawson Selected Research

G S Dawson Research Topics

Disease

Drug/Important Bio-Agent (IBA)